Burleigh "Ol' Stubblebeard" Grimes had thirty-four wins prior to the 1920 season. The year after the ruling he led the league in wins with twenty-two and continued pitching for fourteen more seasons winning a career total of two-hundred seventy games.
On April 15, 1959, a young St. Louis Cardinals rookie — and future Hall of Famer — named Bob Gibson made his Major League debut. He would truly dominate the mound, earn a well deserved spot in the National Baseball Hall of Fame and later comment, "Rules or no rules, pitchers are going to throw spitters. It's a matter of survival."
Trivia alert: The last LEGAL spitball win? Pittsburgh Pirates' pitcher Burleigh Grimes on September 10, 1934, who appeared in relief and defeated the New York Giants 9-7.