1921 Strikeouts Leaders Top 25 in the American League
Name	Strikeouts	Team	Rank
Walter Johnson	143	Washington Senators	1
Urban Shocker	132	St. Louis Browns	2
Bob Shawkey	126	New York Yankees	3
Red Faber	124	Chicago White Sox	4
Dutch Leonard	120	Detroit Tigers	5
Waite Hoyt	102	New York Yankees	6
George Mogridge	101	Washington Senators	7
Dixie Davis	100	St. Louis Browns	8
Stan Coveleski	99	Cleveland Indians	9
Sam Jones	98	Boston Red Sox	10
Joe Bush	96	Boston Red Sox	11
Slim Harriss	92	Philadelphia Athletics	12
Herb Pennock	91	Boston Red Sox	13
Duster Mails	87	Cleveland Indians	14
Bill Bayne	82	St. Louis Browns	15
Dickey Kerr	80	Chicago White Sox	16
Ray Caldwell	76	Cleveland Indians	17
Allen Sothoron	72	St. Louis Browns	18
		Boston Red Sox
		Cleveland Indians
Eric Erickson	71	Washington Senators	19
Eddie Rommel	71	Philadelphia Athletics
Carl Mays	70	New York Yankees	21
Hooks Dauss	68	Detroit Tigers	22
Howard Ehmke	68	Detroit Tigers
Dave Keefe	68	Philadelphia Athletics
Red Oldham	67	Detroit Tigers	25
Name	Strikeouts	Team	Rank

	Jose Cruz of the Houston Astros had his number twenty-five retired on October 3, 1992, and became the first Major League player with that particular retired number. Future Hall of Famer Sammy Sosa is best known for wearing number twenty-one; however, when the young slugger played for the Chicago White Sox (1989-1991) he only wore number twenty-five. The first player from the Angels franchise (they were the California Angels at the time) to wear the number twenty-five was Bob Perry.