1980 Strikeouts Leaders Top 25 in the American League
Name	Strikeouts	Team	Rank
Len Barker	187	Cleveland Indians	1
Mike Norris	180	Oakland Athletics	2
Ron Guidry	166	New York Yankees	3
Floyd Bannister	155	Seattle Mariners	4
Dennis Leonard	155	Kansas City Royals
Jim Clancy	152	Toronto Blue Jays	6
Jerry Koosman	149	Minnesota Twins	7
Steve Stone	149	Baltimore Orioles
Moose Haas	146	Milwaukee Brewers	9
Jon Matlack	142	Texas Rangers	10
Gaylord Perry	135	Texas Rangers	11
		New York Yankees
Britt Burns	133	Chicago White Sox	12
Rudy May	133	New York Yankees
Fergie Jenkins	129	Texas Rangers	14
Mike Flanagan	128	Baltimore Orioles	15
Dennis Eckersley	121	Boston Red Sox	16
Matt Keough	121	Oakland Athletics
Scott McGregor	119	Baltimore Orioles	18
Brian Kingman	116	Oakland Athletics	19
Tom Underwood	116	New York Yankees
Steve McCatty	114	Oakland Athletics	21
Larry Gura	113	Kansas City Royals	22
Frank Tanana	113	California Angels
Jack Morris	112	Detroit Tigers	24
Richard Dotson	109	Chicago White Sox	25
Name	Strikeouts	Team	Rank

	Jim Thome wore number twenty-five since he first came up with the Cleveland Indians making him the franchise record holder for that particular number (Mike Garcia is second). Future Hall of Famer Sammy Sosa is best known for wearing number twenty-one; however, when the young slugger played for the Chicago White Sox (1989-1991) he only wore number twenty-five. Jose Cruz of the Houston Astros had his number twenty-five retired on October 3, 1992, and became the first Major League player with that particular retired number.