2006 Runs Leaders Top 25 in the American League
Name	Runs	Team	Rank
Grady Sizemore	134	Cleveland Indians	1
Derek Jeter	118	New York Yankees	2
Johnny Damon	115	New York Yankees	3
David Ortiz	115	Boston Red Sox
Alex Rodriguez	113	New York Yankees	5
Ichiro Suzuki	110	Seattle Mariners	6
Jim Thome	108	Chicago White Sox	7
Nick Swisher	106	Oakland Athletics	8
Troy Glaus	105	Toronto Blue Jays	9
Jermaine Dye	103	Chicago White Sox	10
Raul Ibanez	103	Seattle Mariners
Mike Cuddyer	102	Minnesota Twins	12
Gary Matthews, Jr.	102	Texas Rangers
Carlos Guillen	100	Detroit Tigers	14
Travis Hafner	100	Cleveland Indians
Kevin Youkilis	100	Boston Red Sox
Mark Teixeira	99	Texas Rangers	17
Miguel Tejada	99	Baltimore Orioles
Tadahito Iguchi	97	Chicago White Sox	19
Paul Konerko	97	Chicago White Sox
Justin Morneau	97	Minnesota Twins
Melvin Mora	96	Baltimore Orioles	22
Orlando Cabrera	95	Los Angeles Angels of Anaheim	23
Chone Figgins	93	Los Angeles Angels of Anaheim	24
Michael Young	93	Texas Rangers
Name	Runs	Team	Rank

	Jose Cruz of the Houston Astros had his number twenty-five retired on October 3, 1992, and became the first Major League player with that particular retired number. Jim Thome wore number twenty-five since he first came up with the Cleveland Indians making him the franchise record holder for that particular number (Mike Garcia is second). Future Hall of Famer Sammy Sosa is best known for wearing number twenty-one; however, when the young slugger played for the Chicago White Sox (1989-1991) he only wore number twenty-five.